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Age is a strong prognostic factor affectingsurvival for all brain tumor patients (Davis et al., 1999).The 5-year survival rate for patients with a GBM is about20% in patients younger than 35 years, 10% in patientsaged 35–54, and only 1% in patients 55 years and older.This is now known to at least partially refl ect fundamen-tal differences in tumor biology (Burger and Green, 1987;Roa et al., 2009). Itsoverall average bone-to-serum concentration ratio was 0.32 (range 0.09–0.55, 10min to6.5h post dose) in five studies that reported concentrations in serum and uninfected boneand in which the majority of samples were above the detection limit [13]. Poor patients are more likely to receive a diagnosis of schizophrenia than richerpatients, who are more likely to receive a less stigmatizing neurotic label such as one of the affec-tive disorders (depression, mania or manic-depression). For most observational studies, differences in potentialconfounding factors can only be allowed (adjusted) for at the end of thestudy, during the statistical analysis. She denies any pre-vious treatments for ear problems. Females, on the other hand, have toinherit abnormal alleles from both parents

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